KEGG   Mycobacterium tuberculosis H37Rv: Rv3051c
Entry
Rv3051c           CDS       T00015                                 
Symbol
nrdE
Name
(RefSeq) ribonucleoside-diphosphate reductase subunit alpha
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00230  Purine metabolism
mtu00240  Pyrimidine metabolism
mtu01100  Metabolic pathways
mtu01232  Nucleotide metabolism
Module
mtu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
mtu_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    Rv3051c (nrdE)
   00240 Pyrimidine metabolism
    Rv3051c (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:mtu03400]
    Rv3051c (nrdE)
Enzymes [BR:mtu01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     Rv3051c (nrdE)
DNA repair and recombination proteins [BR:mtu03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    Rv3051c (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-GeneID: 888869
NCBI-ProteinID: NP_217567
TubercuList: Rv3051c
UniProt: P9WH75
Position
complement(3412085..3414166)
AA seq 693 aa
MLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYS
RNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGD
TALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLS
KRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHA
HHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVP
FADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGK
ITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRA
LTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTV
LYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIP
TQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVY
YPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQI
YAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
NT seq 2082 nt   +upstreamnt  +downstreamnt
atgctgaacctgtacgacgcggacggcaagatccagttcgacaaggatcgggaagcagcc
caccagtactttttgcagcatgtcaatcagaacacggtcttcttccataatcaggacgag
aagctcgactacctgatccgcgagaattactacgagcgtgaggttctcgaccagtactcg
cgcaacttcgtcaagacgctgctagaccgcgcctacgccaaaaagttccggtttccgacg
tttttgggtgcgttcaagtactacacctcctacacgctgaaaacctttgacgggaagcgc
tatctggagcgcttcgaggaccgcgtggtcatggtggcgctaacgttggccgccggcgat
accgcacttgccgagctgctggtcgacgagatcatcgacggccgcttccagcccgccaca
ccgacgtttttgaattctggcaagaagcagcgcggggagcccgtgagctgttttttgctt
cgcgtcgaagacaacatggagtcgatcggacggtcgatcaactccgcgctgcagctatcc
aagcgtggcgggggagtggcgttgctgctgaccaacattcgcgagcacggcgcgccgatc
aagaacatcgagaaccagtcctcgggcgtcatccccatcatgaagttgctggaggatgcg
ttctcctacgccaaccagctgggcgctcgtcaaggtgccggcgcggtgtacctgcacgcc
catcaccccgacatctaccgattcctggacaccaagcgtgagaacgccgacgagaagatc
cggatcaagacgctgagtctgggggtggtgatccccgacatcaccttcgagttggccaag
cgcaacgatgacatgtacctgttctcgccctacgatgtcgagcgggtctacggtgtgccg
ttcgctgacatctcggtcaccgagaagtactacgaaatggtcgatgacgcgcgcatccgc
aagaccaagatcaaggcacgggagttcttccagacgctggccgagctgcagttcgagtcc
ggctacccctatatcatgttcgaagacaccgtcaatcgcgctaatccaattgatggcaag
atcacgcacagcaacctgtgctcggagatcctgcaagtgtctacgccgtcattgttcaac
gaggacttgtcgtatgccaaagtgggcaaagacatttcgtgcaacctggggtcgctgaac
atcgccaagacgatggactcgccggacttcgcgcagacgatcgaggtggcgatccgcgcg
ttgaccgcggtgagcgaccaaacccatatcaagtcggtgccctcaatcgagcagggcaac
aacgactcccacgcgatcgggctaggacagatgaacctgcacggctacctggcccgggaa
cgcatcttctacggatccgacgaaggcatcgacttcaccaacatctacttctatacggtg
ctgtatcacgcgttgcgggcatccaaccgcatcgcgatcgaacgcggcacgcacttcaag
ggtttcgagcggtccaagtacgcgtccggggaattcttcgacaagtacaccgaccagatt
tgggagccgaagacccagaaggtacgccagctgttcgccgacgccggcatccgcatccca
acgcaggacgactggcgtcggctcaaggagtcggtgcaagcgcacggcatctacaaccag
aacctgcaggcggtgccgccgaccgggtcgatttcctacatcaaccattcgacgtcgtcg
attcacccgatcgtgtcgaaggtcgagatccgcaaggaaggcaagatcgggcgggtctac
tacccggcgccgtatatgaccaacgacaacctggagtactacgaagacgcctacgagatc
ggttacgagaagatcatcgacacctacgcggcggccacccagcatgtggatcaagggctt
tcgctgacgttgttcttcaaagacaccgccaccacccgcgacgtgaacaaggcgcagatt
tacgcctggcgcaaggggatcaagacgctgtactacatccggctgcggcagatggcgttg
gagggcaccgaggtcgagggttgcgtgtcctgcatgctgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (42)   

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